Patient Information on L OTEMAX (loteprednol etabonate)

 Company: Bausch & Lomb Incorporated

Uses of this medicine: After an eye surgery, you require Lotemax to prevent the case of severe inflammatory reaction because during surgery the normal layers of cells get breached which could lead to complications. It is usable in both men and women.

Dosage form: it is an ophthalmic gel containing loteprednol etabonate as an active which is responsible for the pharmacological actions.

Dosing: as prescribed by your ophthalmologist.

Correct usage: before you instill the product into your eyes, make sure your hands are clean and that the bottle is shaken well. Do not touch the tip or end of the bottle to dirty places to prevent the transfer of germs to the eyes. Always remember to take out your contact lenses before using the drug. Place it in a cool place.


Lotemax is contra-indicated in viral infections e.g. varicella, so if you develop any sort of an infection during its use, readily inform your doctor. Do not use Lotemax if you have glaucoma or any other such condition that is raising the pressure in your eyes. Consult medical help if your eyes get very irritating, painful, red or watery on the use of Lotemax.

Warnings: If you are recommended to use Lotemax for a prolonged period, have your eyes checked after 10 days to ensure that this drug is not causing any negative effects on your vision. If you feel any change in your sight, talk to your doctor as this drug can lead to cataracts. Never put the product with a contact lens in as it could harm and damage the contacts. Lotemax being a corticosteroid can delay the healing and make you prone to infections.

Adverse effects: Below mentioned conditions are the side effects of Lotemax;

Sensitivity to light, glaucoma, cataracts, increased pressure, damage to the nerves, opportunistic infections, itching, burning, redness, and stinging in the eyes, late wound healing.

During pregnancy: It belongs to the category C. Only administer Lotemax if your doctor prescribes it.

During lactation: Not to be used by nursing mothers unless truly required and recommended by the doctor.

In children: Corticosteroids can stunt the growth and development of children, hence not to be used by young people.

In elderlies: It is considered safe in this population of patients.

Toxicology: In pregnant rats and mice, systemic administration of loteprednol etabonate caused bone deformations and arterial abnormalities and spinal defects. In lactating animals, it stopped the young’s growth and decreased its survival chances. It was not discovered lethal or destructive to qualities and generation of the creatures.

Mechanism of action: It stops and lessens the inflammatory process by preventing the movement of leukocytes, prostaglandins to the affected areas. It also impedes scar formation, collagen accumulation, dilatation of capillary membranes, fibrin deposition. All these take place by binding of the drug to its glucocorticoid receptors.

Absorption: It has only minimal absorption into the blood when topically applied.

Inform the doctor about your: If you have any sort of infection, eye related problems such as glaucoma or cataracts, if pregnant or breast-feeding, about your past allergies, if you are taking other medicines.

Ingredients: It contains loteprednol etabonate, Purified Water, Tyloxapol, Edetate, glycerin Disodium, and Povidone.




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